Atracurium besylate
Tracrium (atracurium besylate) is a small molecule pharmaceutical. Atracurium besylate was first approved as Tracrium preservative free on 1983-11-23.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| atracurium besylate | ANDA | 2023-11-23 |
Indications
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Clinical
Clinical Trials
31 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Postoperative pain | D010149 | — | G89.18 | — | — | 1 | 1 | 1 | 3 |
| Anesthesia | D000758 | — | — | — | — | — | 1 | 2 | 3 |
| Neuromuscular blockade | D019148 | — | — | — | — | — | 1 | 1 | 2 |
| Postoperative nausea and vomiting | D020250 | EFO_0004888 | — | — | — | — | 1 | 1 | 2 |
| Conduction anesthesia | D000765 | — | — | — | — | — | 1 | — | 1 |
| Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | — | — | 1 | — | 1 |
| Retinal diseases | D012164 | HP_0000479 | H35.9 | — | — | — | 1 | — | 1 |
| Myoclonus | D009207 | HP_0012323 | G25.3 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Premedication | D011292 | — | — | — | 2 | 2 | — | — | 2 |
| Intratracheal intubation | D007442 | — | — | — | 2 | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Radical mastectomy | D015409 | — | — | 1 | 1 | — | — | — | 1 |
| Intraocular pressure | D007429 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | — | — | — | — | 1 | 1 |
| Male breast neoplasms | D018567 | — | — | — | — | — | — | 1 | 1 |
| Swine diseases | D013553 | — | — | — | — | — | — | 1 | 1 |
| Urologic diseases | D014570 | — | N39.9 | — | — | — | — | 1 | 1 |
| Lacrimal duct obstruction | D007767 | — | — | — | — | — | — | 1 | 1 |
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Atracurium besylate |
| INN | atracurium besilate |
| Description | Atracurium besylate is the bisbenzenesulfonate salt of atracurium. It has a role as a nicotinic antagonist and a muscle relaxant. It is a quaternary ammonium salt and an organosulfonate salt. It contains an atracurium. |
| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives: neuromuscular blocking agents |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]2(C)CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)cc1OC.O=S(=O)([O-])c1ccccc1.O=S(=O)([O-])c1ccccc1 |
Identifiers
| PDB | — |
| CAS-ID | 64228-81-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1200527 |
| ChEBI ID | 2915 |
| PubChem CID | 47320 |
| DrugBank | DB00732 |
| UNII ID | 40AX66P76P (ChemIDplus, GSRS) |
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Additional graphs summarizing 336 documents
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Safety
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1,477 adverse events reported
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